Cell Enrichment and Extraction
Biocept has developed the Cell Enrichment and Extraction™ (CEE) technology, which utilizes the company’s proprietary system to capture rare cells in a microfluidic device.
Once captured, these cells remain suitable for molecular diagnosis either as intact cells or after lysis. Captured cells can be assessed morphologically, immunohistochemically, by fluorescent in situ hybridization (FISH) or by a variety of molecular analyses after extraction of the DNA or RNA.
Optimizing CEE for Sample Enrichment
CEE Microfluidics:
Placement of the posts and flow rates developed with mathematical models maximize cell capture in the microelectromechanical systems (MEMS) channel.
CEE Attachment Chemistry:
Specified antibodies are coupled to the base and posts to selectively attach to target cells, creating an enriched cell sample.
